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Tranexamic Acid During Colonic Endoscopic Resection Procedures
Sponsor: Assaf-Harofeh Medical Center
Summary
Colonoscopy with polypectomy reduces the incidence and mortality associated with colon cancer. However, polypectomy is associated with adverse events such as bleeding. Tranexamic acid (TXA) is a synthetic derivative of lysine that exerts antifibrinolytic effects and may prevent bleeding. The investigators aim to evaluate the effect of local TXA on preventing intraprocedural and postprocedural bleeding in patients undergoing endoscopic mucosal resection (EMR) of large colon polyps.
Official title: Usage of Tranexamic Acid During Colonic Endoscopic Resection Procedures for Reduction Intraprocedural and Postprocedural Bleeding
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
200
Start Date
2022-05-01
Completion Date
2026-10-01
Last Updated
2026-01-13
Healthy Volunteers
No
Conditions
Interventions
Tranexamic acid
Submucosal injection of standard solution including TXA during EMR procedure
Standard
Injection of standard solution
Locations (1)
Shamir Medical Center
Be’er Ya‘aqov, Israel