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RECRUITING
NCT05349955
NA

Effects and Safety of Diabetic GUideline Algorithm Implementation Performed by Primary Care Physicians in the Community

Sponsor: Shanghai Zhongshan Hospital

View on ClinicalTrials.gov

Summary

The Effects and Safety of Diabetic GUideline Algorithm Implementation in the Community (GUARD-Community) study is a 2-arm, cluster-randomized control trial to evaluate the effect and safety of guideline algorithm intervention performed by primary care physicians on cardiovascular and renal outcomes in elderly patients with high risk in community.

Official title: Effects and Safety of GUideline Algorithm Based Intervention on CaRdiovascular and Renal Outcomes in Elderly Diabetic Patients With High Cardiovascular Risk in the Community- A Cluster Randomized Controlled Trial (GUARD-Community Study)

Key Details

Gender

All

Age Range

65 Years - Any

Study Type

INTERVENTIONAL

Enrollment

5600

Start Date

2022-11-21

Completion Date

2026-11-30

Last Updated

2025-05-14

Healthy Volunteers

No

Interventions

OTHER

Intensive guideline algorithm implementation

Diabetes guideline pharmacological algorithm will be implemented by primary care physicians in community. In brief, SGLT2i or GLP-1RA will be recommended to control blood glucose in priority when subjects at very high/high CV risk and meet the target HbA1C\<7%, control blood pressure \<130/80mmHg, LDL-c\<1.8mmol/L at very high CV risk patients or \<2.6mmol/L at high CV risk patients, and antiplatelet as secondary prevention of ASCVD.

OTHER

Conventional guideline algorithm implementation

The guideline intervention is based the guidance which the local physicians followed through self learning and education. The management of diabetes paitients will be decided by local physicians.

Locations (13)

Xiangcheng Second People's Hospital

Suzhou, Jaingsu, China

Caohu Community Healthcare Center

Suzhou, Jiangsu, China

Huangqiao Community Healthcare Center

Suzhou, Jiangsu, China

Xiangcheng People's Hospital.

Suzhou, Jiangsu, China

Yuanhe Community Healthcare Center

Suzhou, Jiangsu, China

Xiangcheng Third People's Hospital

Suzhou, Jiangsu, China

Taiping Community Healthcare Center

Suzhou, Jiangsu, China

Yangchenghu People's Hospital

Suzhou, Jiangsu, China

Health Center of Xiangcheng Tourism Resort

Suzhou, Jiangsu, China

Caohu People's Hospital

Suzhou, Jiangsu, China

Dongqiao Community Healthcare Center

Suzhou, Jiangsu, China

Xiangcheng Traditional Chinese Medicine Hospital

Suzhou, Jiangsu, China

Chengyang Community Healthcare Center

Suzhou, Jiangsu, China