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Effects and Safety of Diabetic GUideline Algorithm Implementation Performed by Primary Care Physicians in the Community
Sponsor: Shanghai Zhongshan Hospital
Summary
The Effects and Safety of Diabetic GUideline Algorithm Implementation in the Community (GUARD-Community) study is a 2-arm, cluster-randomized control trial to evaluate the effect and safety of guideline algorithm intervention performed by primary care physicians on cardiovascular and renal outcomes in elderly patients with high risk in community.
Official title: Effects and Safety of GUideline Algorithm Based Intervention on CaRdiovascular and Renal Outcomes in Elderly Diabetic Patients With High Cardiovascular Risk in the Community- A Cluster Randomized Controlled Trial (GUARD-Community Study)
Key Details
Gender
All
Age Range
65 Years - Any
Study Type
INTERVENTIONAL
Enrollment
5600
Start Date
2022-11-21
Completion Date
2026-11-30
Last Updated
2025-05-14
Healthy Volunteers
No
Interventions
Intensive guideline algorithm implementation
Diabetes guideline pharmacological algorithm will be implemented by primary care physicians in community. In brief, SGLT2i or GLP-1RA will be recommended to control blood glucose in priority when subjects at very high/high CV risk and meet the target HbA1C\<7%, control blood pressure \<130/80mmHg, LDL-c\<1.8mmol/L at very high CV risk patients or \<2.6mmol/L at high CV risk patients, and antiplatelet as secondary prevention of ASCVD.
Conventional guideline algorithm implementation
The guideline intervention is based the guidance which the local physicians followed through self learning and education. The management of diabetes paitients will be decided by local physicians.
Locations (13)
Xiangcheng Second People's Hospital
Suzhou, Jaingsu, China
Caohu Community Healthcare Center
Suzhou, Jiangsu, China
Huangqiao Community Healthcare Center
Suzhou, Jiangsu, China
Xiangcheng People's Hospital.
Suzhou, Jiangsu, China
Yuanhe Community Healthcare Center
Suzhou, Jiangsu, China
Xiangcheng Third People's Hospital
Suzhou, Jiangsu, China
Taiping Community Healthcare Center
Suzhou, Jiangsu, China
Yangchenghu People's Hospital
Suzhou, Jiangsu, China
Health Center of Xiangcheng Tourism Resort
Suzhou, Jiangsu, China
Caohu People's Hospital
Suzhou, Jiangsu, China
Dongqiao Community Healthcare Center
Suzhou, Jiangsu, China
Xiangcheng Traditional Chinese Medicine Hospital
Suzhou, Jiangsu, China
Chengyang Community Healthcare Center
Suzhou, Jiangsu, China