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HYDROcortisone Versus Placebo for Severe HospItal-acquired Pneumonia in Intensive Care Patients: the HYDRO-SHIP Study
Sponsor: Instituto de Assistencia Medica ao Servidor Publico Estadual, Sao Paulo
Summary
The use of corticosteroids in patients with severe community pneumonia, bacterial infection which kills lots of patients around the world, reduces the mortality of this infection. However, there are no studies with this type of drug regarding hospital-acquired pneumonia. This is the first multicenter randomized trial to test hydrocortisone plus standard therapy in critical care patients with nosocomial pneumonia. This intervention is inexpensive and may improve the outcome of those patients, besides having an acceptable side effects profile.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
180
Start Date
2022-10-16
Completion Date
2027-02
Last Updated
2025-11-25
Healthy Volunteers
No
Interventions
Hydrocortisone
Corticosteroid
Placebo
Normal saline only
Locations (1)
Hospital do Servidor Publico Estadual
São Paulo, Sao Paulo SP, Brazil