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RECRUITING
NCT05354778
NA

HYDROcortisone Versus Placebo for Severe HospItal-acquired Pneumonia in Intensive Care Patients: the HYDRO-SHIP Study

Sponsor: Instituto de Assistencia Medica ao Servidor Publico Estadual, Sao Paulo

View on ClinicalTrials.gov

Summary

The use of corticosteroids in patients with severe community pneumonia, bacterial infection which kills lots of patients around the world, reduces the mortality of this infection. However, there are no studies with this type of drug regarding hospital-acquired pneumonia. This is the first multicenter randomized trial to test hydrocortisone plus standard therapy in critical care patients with nosocomial pneumonia. This intervention is inexpensive and may improve the outcome of those patients, besides having an acceptable side effects profile.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

180

Start Date

2022-10-16

Completion Date

2027-02

Last Updated

2025-11-25

Healthy Volunteers

No

Interventions

DRUG

Hydrocortisone

Corticosteroid

DRUG

Placebo

Normal saline only

Locations (1)

Hospital do Servidor Publico Estadual

São Paulo, Sao Paulo SP, Brazil