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COMPLETED
NCT05357755
PHASE2

A Study of JNJ-77242113 for the Treatment of Moderate-to-Severe Plaque Psoriasis

Sponsor: Janssen Research & Development, LLC

View on ClinicalTrials.gov

Summary

The purpose of the study is to evaluate the efficacy of an oral tablet formulation of JNJ-77242113 compared with placebo in participants with moderate-to-severe plaque psoriasis.

Official title: A Phase 2a Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of an Oral Tablet Formulation of JNJ-77242113 for the Treatment of Moderate-to-Severe Plaque Psoriasis

Key Details

Gender

All

Age Range

18 Years - 75 Years

Study Type

INTERVENTIONAL

Enrollment

90

Start Date

2022-06-13

Completion Date

2023-04-10

Last Updated

2026-05-05

Healthy Volunteers

No

Interventions

DRUG

JNJ-77242113

JNJ-77242113 will be administered orally as delayed release tablets.

DRUG

Placebo

Matching placebo will be administered orally as delayed release tablets.

Locations (34)

Stoll Dermatology

Beverly Hills, California, United States

Northshore University Healthsystem

Skokie, Illinois, United States

Epiphany Dermatology of Kansas, LLC

Overland Park, Kansas, United States

Dermatology Specialists

Louisville, Kentucky, United States

Lawrence J Green MD LLC

Rockville, Maryland, United States

ActivMed Practices and Research

Beverly, Massachusetts, United States

ActivMed Practices and Research

Portsmouth, New Hampshire, United States

Windsor Dermatology, PC

East Windsor, New Jersey, United States

Unity Clinical Research

Oklahoma City, Oklahoma, United States

The Pennsylvania Centre for Dermatology, LLC

Exton, Pennsylvania, United States

Health Concepts

Rapid City, South Dakota, United States

Arlington Center for Dermatology

Arlington, Texas, United States

Dermatology Research Institute Inc

Calgary, Alberta, Canada

The Guenther Dermatology Research Centre

London, Ontario, Canada

Lynderm Research Inc.

Markham, Ontario, Canada

DermEdge Research

Mississauga, Ontario, Canada

Toronto Research Centre

Toronto, Ontario, Canada

CHRU Brest - Hopital Morvan

Brest, France

CHU de Grenoble Hopital Albert Michallon

La Tronche, France

CHU de Nice Hopital de l Archet

Nice, France

Polyclinique de Courlancy

Reims, France

Hautarztpraxis

Bramsche, Germany

Universitatsklinikum Carl Gustav Carus Dresden

Dresden, Germany

Privatpraxis Dr. Hilton & Partner

Düsseldorf, Germany

Universitatsklinikum Frankfurt

Frankfurt am Main, Germany

Universitatsklinikum Schleswig Holstein Campus Lubeck

Lübeck, Germany

Universitatsklinikum Munster

Münster, Germany

Universitaetsmedizin Rostock

Rostock, Germany

Specderm Poznanska sp j

Bialystok, Poland

Specjalistyczny gabinet dermatologiczny Aplikacyjno Badawczy Marek Brzewski Pawel Brzewski Spolka Cywilna

Krakow, Poland

Centrum Terapii Wspolczesnej J M Jasnorzewska Spolka Komandytowo Akcyjna

Lodz, Poland

Hosp. Univ. de Cruces

Barakaldo, Spain

Hosp. Univ. San Cecilio

Granada, Spain

Hosp. Virgen Macarena

Seville, Spain