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Global collaboRAtion on CIC-DUX4, BCOR-CCN3, High-grade Undifferentiated Round Cell Sarcoma (URCS) Project
Sponsor: Istituto Ortopedico Rizzoli
Summary
Experimental study with biological material : case series review of clinical and histological data
Key Details
Gender
All
Age Range
Any - Any
Study Type
OBSERVATIONAL
Enrollment
260
Start Date
2019-06-11
Completion Date
2028-12-31
Last Updated
2025-05-30
Healthy Volunteers
Not specified
Conditions
Interventions
data collection and analysis on Formalin-fixed paraffin embedded tissue and/or frozen tumoral tissue
Formalin-fixed paraffin embedded tissue and/or frozen tumoral tissue of cases negative for all Ewing's sarcoma molecular fusions, will be analyzed for the presence of CIC-DUX4 / BCOR-CCNB3 translocations fusion at each Institution. Treatment, outcome, and prognostic factors will be related with the molecular re-classification.
Locations (1)
IRCCs Istituto Ortopedico Rizzoli
Bologna, BO, Italy