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A Study of the Effectiveness of Cabozantinib in Combination With Nivolumab as First-line Treatment of Advanced Renal Cell Carcinoma (aRCC) in Adults
Sponsor: Ipsen
Summary
The purpose of this study is to collect data to describe the safety and effectiveness of cabozantinib and nivolumab in combination as a first-line treatment in adults with aRCC with clear cell-component, according to real-world clinical practice. The decision to prescribe cabozantinib and nivolumab in combination will be made prior to, and independently from, the decision to enrol the participant in study.
Official title: A Prospective Observational International Study of Cabozantinib Tablets in Combination With Nivolumab as First-line Treatment of Advanced Renal Cell Carcinoma in Adults
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
311
Start Date
2022-09-26
Completion Date
2026-11-30
Last Updated
2026-04-01
Healthy Volunteers
No
Conditions
Locations (66)
CHU St Pierre & Brugmann
Brussels, Belgium
Jessa Ziekenhuis
Hasselt, Belgium
CHU Namur Mont-Godinne
Yvoir, Belgium
Centre Hospitalier Universitaire (CHU) de Angers
Angers, France
Hopital de Mercy- CHR Metz Thionville
Ars-Laquenexy, France
Institut Ste Catherine - Institut du Cancer Avignon Provence
Avignon, France
Centre Hospitalier Régional Universitaire de Besançon - Jean Minjoz
Besançon, France
ICONE
Bezannes, France
Groupe Hospitalier Saint-André (Bordeaux)
Bordeaux, France
Institut Bergonié
Bordeaux, France
Centre Hospitalier de Boulogne-sur-mer
Boulogne-sur-Mer, France
Centre Hospitalier Fleyriat
Bourg-en-Bresse, France
Centre Finisterien de Radiotherapie et d'Oncologie
Brest, France
Centre d'Urologie Site Médipole - Centre Catalan d'Urologie
Cabestany, France
Centre de Lutte Contre le Cancer Jean PERRIN
Clermont-Ferrand, France
Centre Hospitalier Universitaire de Clermont-Ferrand - Gabriel-Montpied
Clermont-Ferrand, France
Centre Hospitalier Universitaire (CHU) Henri Mondor
Créteil, France
Centre Georges François Leclerc
Dijon, France
Institut de Cancérologie de Bourgogne
Dijon, France
Centre Hospitalier Annecy Genevois
Épagny, France
Centre Hospitalier intercommunal Saint Raphaël Frejus
Fréjus, France
Centre Hospitalier Départemental Vendée
La Roche-sur-Yon, France
Groupe Hospitalier De La Rochelle - Ré - Aunis
La Rochelle, France
Centre Hospitalier Universitaire Grenoble Alpes
La Tronche, France
Hôpital Privé Le Bois
Lille, France
Hopital Privé Jean Mermoz
Lyon, France
Centre Hospitalier Universitaire (CHU) de Nantes - Hôtel-Dieu
Nantes, France
Centre Hospitalier Régional D'orléans
Orléans, France
Centre Hospitalier Tenon
Paris, France
Hopital Bichat -Claud Bernard
Paris, France
Hôpital Européen Georges Pompidou (HEGP)
Paris, France
Hôpital Pitié-Salpétrière
Paris, France
Centre Hospitalier Universitaire (CHU) de Poitiers
Poitiers, France
CHU Charles Nicolle
Rouen, France
Clinique Mathilde Oncologie médicale
Rouen, France
Centre d'Oncologie de l'Estuaire
Saint-Nazaire, France
ICANS - Institut de cancérologie Strasbourg Europe
Strasbourg, France
Hospital Foch - Oncology Service
Suresnes, France
Hospital Foch - Urology Service
Suresnes, France
Centre Hospitalier Régional Universitaire de (CHRU) de Tours - Hôpital Bretonneau
Tours, France
CH Dentellières
Valenciennes, France
Institut de Cancérologie de Lorraine Alexis Vautrin
Vandœuvre-lès-Nancy, France
General Hospital of Athens Alexandra
Athens, Greece
Henry Dunant Hospital
Athens, Greece
ATTIKO University Hospital
Chaïdári, Greece
Papageorgiou General Hosp of Thessaloniki
Thessaloniki, Greece
Ospedale Generale Provincial
Macerata, Italy
Istituto Romagnolo per lo Studio dei Tumori "Dino Amadori", IRCCS - Oncologia
Meldola, Italy
Fondazione IRCCS, Istituto Nazionale dei Tumori
Milan, Italy
Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale"
Naples, Italy
AOU San Luigi Gonzaga
Orbassano, Italy
IOV - Istituto Oncologico Veneto - IRCCS - Ospedale Busonera
Padova, Italy
P.O Santa Maria delle Grazie, ASL Napoli 2 Nord
Pozzuoli, Italy
Ospedale "Santa Maria delle Croci" di Ravenna
Ravenna, Italy
Ospedale San Camillo Forlanini
Roma, Italy
Policlinico Universitario Campus Biomedico
Roma, Italy
PU A.Gemelli, Università Cattolica del Sacro Cuore
Roma, Italy
Akershus Universitetssykehus
Lørenskog, Norway
King Abdulaziz Medical City - Jeddah
Jeddah, Saudi Arabia
King Abdulaziz Medical City- Riyadh
Riyadh, Saudi Arabia
Chonnam National University Hwasun Hospital
Jeongnam, South Korea
Samsung Medical Center
Seoul, South Korea
Seoul St Mary's Hospital
Seoul, South Korea
Severance Hospital, Yonsei University Health System
Seoul, South Korea
Belfast City Hospital
Belfast, United Kingdom
Edinburgh Cancer Centre, Western General Hospital
Edinburgh, United Kingdom