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PV Loop & Coarctation Study
Sponsor: University of Minnesota
Summary
Coarctation of the aorta accounts for 4-7% of all congenital heart disease. While stent therapy, when feasible, is the standard of care for coarctation, it may not completely improve the work (and afterload) of the heart due to its effects on the elasticity of the aorta. This study will provide the information needed to understand the effects of current management on the cardiac mechanics and work.
Official title: Assessment of the Impact of Transcatheter Stenting of Aortic Coarctation on the Left Ventricular Afterload and Work Using Left Ventricular Pressure Volume Loops
Key Details
Gender
All
Age Range
6 Years - Any
Study Type
OBSERVATIONAL
Enrollment
21
Start Date
2019-06-04
Completion Date
2026-12-31
Last Updated
2026-04-08
Healthy Volunteers
No
Conditions
Interventions
Pressure-volume loop catheter
The cardiac catheterization procedure will be done according to standard protocol as part of the standard clinical care. This has become the standard of care in any patient in which it feasible and is performed with low risk.
Locations (7)
Children's Hospital of Los Angeles
Los Angeles, California, United States
Children's Hospital of Boston
Boston, Massachusetts, United States
Helen DeVos Children's Hospital
Grand Rapids, Michigan, United States
University of Minnesota
Minneapolis, Minnesota, United States
Children's Mercy Hospital
Kansas City, Missouri, United States
Cincinnati Children's Hospital
Cincinnati, Ohio, United States
University of Texas-Southwestern
Dallas, Texas, United States