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NCT05362903

A Non-interventional Implementation Study to Evaluate Treatment With Inclisiran (Leqvio®) and Other Lipid Lowering Treatments in a Real-world Setting

Sponsor: Novartis Pharmaceuticals

View on ClinicalTrials.gov

Summary

This was a multicenter, non-randomized, non-interventional three-cohort study with prospective collection of primary data of treatment with newly initiated oral lipid lowering treatment on top of a statin (Oral LLT cohort), newly initiated Inclisiran (Inclisiran cohort) and newly initiated Inclisiran on top of lipid apheresis (Apheresis plus Inclisiran cohort) in routine clinical care. All procedures, treatment adaptions and laboratory assessments were part of clinical routine and conducted independent of this study.

Official title: A Non-interventional Implementation Study to Evaluate Treatment With Inclisiran (Leqvio®) and Other Lipid Lowering Treatments in a Real-world Setting (VICTORION-Implement)

Key Details

Gender

All

Age Range

18 Years - 100 Years

Study Type

OBSERVATIONAL

Enrollment

1868

Start Date

2022-01-28

Completion Date

2025-11-28

Last Updated

2026-09-24

Healthy Volunteers

No

Interventions

OTHER

Inclisiran

Prospective observational cohort study. There is no treatment allocation. Patients administered Inclisiran by prescription will be enrolled.

Locations (121)

Novartis Investigative Site

Freudenstadt, Baden-Wurttemberg, Germany

Novartis Investigative Site

Heidelberg, Baden-Wurttemberg, Germany

Novartis Investigative Site

Kirchheim unter Teck, Baden-Wurttemberg, Germany

Novartis Investigative Site

Konstanz, Baden-Wurttemberg, Germany

Novartis Investigative Site

Ulm, Baden-Wurttemberg, Germany

Novartis Investigative Site

Bayreuth, Bavaria, Germany

Novartis Investigative Site

Coburg, Bavaria, Germany

Novartis Investigative Site

Dachau, Bavaria, Germany

Novartis Investigative Site

Deggendorf, Bavaria, Germany

Novartis Investigative Site

Füssen, Bavaria, Germany

Novartis Investigative Site

Grünwald, Bavaria, Germany

Novartis Investigative Site

Landshut, Bavaria, Germany

Novartis Investigative Site

Marktoberdorf, Bavaria, Germany

Novartis Investigative Site

Muehldorf Am Inn, Bavaria, Germany

Novartis Investigative Site

Munich, Bavaria, Germany

Novartis Investigative Site

Munich, Bavaria, Germany

Novartis Investigative Site

Munich, Bavaria, Germany

Novartis Investigative Site

Neumarkt in der Oberpfalz, Bavaria, Germany

Novartis Investigative Site

Nuremberg, Bavaria, Germany

Novartis Investigative Site

Würzburg, Bavaria, Germany

Novartis Investigative Site

Burg, Brandenburg, Germany

Novartis Investigative Site

Eberswalde, Brandenburg, Germany

Novartis Investigative Site

Potsdam, Brandenburg, Germany

Novartis Investigative Site

Schwedt, Brandenburg, Germany

Novartis Investigative Site

Kassel, Hesse, Germany

Novartis Investigative Site

Offenbach, Hesse, Germany

Novartis Investigative Site

Rotenburg (Wümme), Lower Saxony, Germany

Novartis Investigative Site

Winsen, Lower Saxony, Germany

Novartis Investigative Site

Stralsund, Mecklenburg-Vorpommern, Germany

Novartis Investigative Site

Aachen, North Rhine-Westphalia, Germany

Novartis Investigative Site

Detmold, North Rhine-Westphalia, Germany

Novartis Investigative Site

Mülheim, North Rhine-Westphalia, Germany

Novartis Investigative Site

Münster, North Rhine-Westphalia, Germany

Novartis Investigative Site

Münster, North Rhine-Westphalia, Germany

Novartis Investigative Site

Siegen, North Rhine-Westphalia, Germany

Novartis Investigative Site

Ingelheim, Rhineland-Palatinate, Germany

Novartis Investigative Site

Kaiserslautern, Rhineland-Palatinate, Germany

Novartis Investigative Site

Pirmasens, Rhineland-Palatinate, Germany

Novartis Investigative Site

Chemnitz, Saxony, Germany

Novartis Investigative Site

Chemnitz, Saxony, Germany

Novartis Investigative Site

Görlitz, Saxony, Germany

Novartis Investigative Site

Hohenstein-Ernstthal, Saxony, Germany

Novartis Investigative Site

Leipzig, Saxony, Germany

Novartis Investigative Site

Leipzig, Saxony, Germany

Novartis Investigative Site

Leipzig, Saxony, Germany

Novartis Investigative Site

Pirna, Saxony, Germany

Novartis Investigative Site

Halle, Saxony-Anhalt, Germany

Novartis Investigative Site

Halle, Saxony-Anhalt, Germany

Novartis Investigative Site

Quedlinburg, Saxony-Anhalt, Germany

Novartis Investigative Site

Salzatal, Saxony-Anhalt, Germany

Novartis Investigative Site

Wittenberg, Saxony-Anhalt, Germany

Novartis Investigative Site

Greiz, Thuringia, Germany

Novartis Investigative Site

Jena, Thuringia, Germany

Novartis Investigative Site

Altenburg, Germany

Novartis Investigative Site

Aue, Germany

Novartis Investigative Site

Bad Homburg, Germany

Novartis Investigative Site

Bad Nauheim, Germany

Novartis Investigative Site

Berlin, Germany

Novartis Investigative Site

Berlin, Germany

Novartis Investigative Site

Berlin, Germany

Novartis Investigative Site

Berlin, Germany

Novartis Investigative Site

Biedenkopf, Germany

Novartis Investigative Site

Borsdorf, Germany

Novartis Investigative Site

Brilon, Germany

Novartis Investigative Site

Brüel, Germany

Novartis Investigative Site

Chemnitz, Germany

Novartis Investigative Site

Chemnitz, Germany

Novartis Investigative Site

Cloppenburg, Germany

Novartis Investigative Site

Cologne, Germany

Novartis Investigative Site

Cologne, Germany

Novartis Investigative Site

Cuxhaven, Germany

Novartis Investigative Site

Dachau, Germany

Novartis Investigative Site

Darmstadt, Germany

Novartis Investigative Site

Dessau, Germany

Novartis Investigative Site

Dresden, Germany

Novartis Investigative Site

Ehingen, Germany

Novartis Investigative Site

Ehringshausen, Germany

Novartis Investigative Site

Eisfeld, Germany

Novartis Investigative Site

Frechen, Germany

Novartis Investigative Site

Fürth, Germany

Novartis Investigative Site

Greifswald, Germany

Novartis Investigative Site

Günzburg, Germany

Novartis Investigative Site

Hamburg, Germany

Novartis Investigative Site

Hamburg, Germany

Novartis Investigative Site

Hamburg, Germany

Novartis Investigative Site

Hamburg, Germany

Novartis Investigative Site

Haßloch, Germany

Novartis Investigative Site

Heide, Germany

Novartis Investigative Site

Kiel, Germany

Novartis Investigative Site

Ludwigshafen, Germany

Novartis Investigative Site

Mainz, Germany

Novartis Investigative Site

Mannheim, Germany

Novartis Investigative Site

Markkleeberg, Germany

Novartis Investigative Site

Moers, Germany

Novartis Investigative Site

München, Germany

Novartis Investigative Site

Münster, Germany

Novartis Investigative Site

Naumburg, Germany

Novartis Investigative Site

Neuruppin, Germany

Novartis Investigative Site

Olpe, Germany

Novartis Investigative Site

Oranienburg, Germany

Novartis Investigative Site

Oschatz, Germany

Novartis Investigative Site

Osnabrück, Germany

Novartis Investigative Site

Osnabrück, Germany

Novartis Investigative Site

Papenburg, Germany

Novartis Investigative Site

Rendsburg, Germany

Novartis Investigative Site

Riesa, Germany

Novartis Investigative Site

Rostock, Germany

Novartis Investigative Site

Schwandorf in Bayern, Germany

Novartis Investigative Site

Speyer, Germany

Novartis Investigative Site

Stadtlohn, Germany

Novartis Investigative Site

Trier, Germany

Novartis Investigative Site

Ulm, Germany

Novartis Investigative Site

Ulm, Germany

Novartis Investigative Site

Ulm, Germany

Novartis Investigative Site

Wermsdorf, Germany

Novartis Investigative Site

Wesel, Germany

Novartis Investigative Site

Winterberg, Germany

Novartis Investigative Site

Wismar, Germany

Novartis Investigative Site

Wuppertal, Germany

Novartis Investigative Site

Würzburg, Germany

Novartis Investigative Site

Zwiesel, Germany