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Effect of Breastfeeding on Lipid Profile and Cardiovascular Risk Markers in Women With Familial Hypercholesterolemia
Sponsor: Oslo University Hospital
Summary
The study aims to investigate the effects of breastfeeding on lipid profile and cardiovascular risk markers in women with familial hypercholesterolemia (FH) compared to women without FH. Women with FH will be recruited in Norway, the Netherlands, and the Czech Republic. Women without FH will be recruited in Norway. Women with and without FH who are pregnant or planning pregnancy will be recruited, and will be invited to repeated study visits from the end of pregnancy and through the first year after delivery. Blood samples and data on anthropometry, health, pregnancy, lifestyle and diet will be collected. Statin transfer into breast milk will also be measured in breast milk samples collected when the women end breastfeeding the child and start statin treatment.
Official title: Effect of Breastfeeding on Lipid Profile and Cardiovascular Risk Markers in Women With Familial Hypercholesterolemia (FH-FEMINA)
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
50
Start Date
2022-05-01
Completion Date
2027-08-31
Last Updated
2026-02-05
Healthy Volunteers
Yes
Conditions
Locations (4)
Centre of Cardiovascular Surgery and Transplantation
Brno, Czechia
Third Department of Internal Medicine, General University Hospital, First Faculty of Medicine, Charles University
Prague, Czechia
Department of Internal Medicine, Erasmus MC Cardiovascular Institute
Rotterdam, Netherlands
Oslo University Hospital
Oslo, Norway