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Personalized Perioperative Analgesia Platform (PPAP) for Pediatric Spine Fusion Surgery (sIRB)
Sponsor: Senthil Sadhasivam
Summary
The purpose of this collaborative CTSA application is to develop an innovative perioperative precision analgesia platform (PPAP) to improve analgesia and reduce serious immediate and long-term adverse outcomes of perioperative opioids in children undergoing painful surgery.
Key Details
Gender
All
Age Range
10 Years - 21 Years
Study Type
INTERVENTIONAL
Enrollment
300
Start Date
2022-09-20
Completion Date
2026-09
Last Updated
2025-09-19
Healthy Volunteers
No
Conditions
Interventions
Preoperative Genotyping
Genotype based risk prediction and personalized pain management
Locations (3)
University of California
San Francisco, California, United States
Riley Children's Hospital
Indianapolis, Indiana, United States
UPMC Children's Hospital
Pittsburgh, Pennsylvania, United States