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ACTIVE NOT RECRUITING
NCT05369182

Multicenter Registry of Coronary Flow-Derived Indexes for Coronary Microvascular Disease (Multicenter FLOW-CMD Registry)

Sponsor: Samsung Medical Center

View on ClinicalTrials.gov

Summary

Multicenter FLOW-CMD registry is a prospective, multi-center, registry study. The aim of the study is to evaluate prognostic implications of coronary microvascular disease (CMD) in patients with ischemic heart disease (IHD) undergoing revascularization decision using FFR or other non-hyperemic pressure ratios.

Official title: Prospective Registry of Coronary Flow-Derived Indexes in Patients With Coronary Artery Disease

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

1003

Start Date

2022-04-22

Completion Date

2027-12-31

Last Updated

2026-02-12

Healthy Volunteers

No

Interventions

DIAGNOSTIC_TEST

Invasive physiologic assessment

All coronary physiologic parameters are measured following diagnostic angiography. Resting pd/pa, FFR, CFR and IMR will be calculated using coronary physiologic parameters. In patients treated by PCI, post-PCI physiologic assessment including CFR, IMR, and FFR will be performed.

DIAGNOSTIC_TEST

Intravascular imaging

By the operator's discretion, stent-optimization will be performed under intravascular imaging devices (IVUS \[Boston Scientific, Natick, Massachusetts, USA\] or OCT \[Abbott Vascular\], St. Paul, MN, USA\]).

Locations (7)

Chonnam National University Hospital

Gwangju, South Korea

Chosun University Hospital

Gwangju, South Korea

Gyeongsang National University Hospital

Jinju, South Korea

Seoul National University Bundang Hospital

Seongnam, South Korea

Samsung Medical Center

Seoul, South Korea

Seoul National University Boramae Medical Center

Seoul, South Korea

Seoul St. Mary's Hospital

Seoul, South Korea