Clinical Research Directory

Inclusion Criteria: PCI patients \>18 years of age and meeting 1 major criterion or 2 minor criteria of the ARC-HBR The ARC-HBR major criteria included: * long-term use of oral anticoagulants; * severe or end-stage chronic kidney disease \[eGFR \<30 ml/(min\*1.73m2 )\]; * hemoglobin \<11 g/dl, spontaneous bleeding requiring hospitalization or transfusion within the past 6 months or at any time; * chronic bleeding constitutional; * cirrhosis with portal hypertension spontaneous bleeding requiring hospitalization or transfusion within the past 6 months or at any time; * moderate to severe baseline thrombocytopenia (platelets \<100×10\^9/L); chronic bleeding constitutional; * cirrhosis with portal hypertension; * active malignancy within the past 12 months (excluding non-melanoma skin cancer); * previous spontaneous brain hemorrhage (at any time); * traumatic brain hemorrhage within the past 12 months; * within the past 6 months moderate or severe ischemic stroke within the past 6 months; * the presence of cerebral arteriovenous malformation; * recent major surgery or major trauma within 30 days prior to PCI; * and major non-delayable surgery during DAPT. Secondary criteria included: * age ≥75 years; * moderate chronic kidney disease \[30 ml/(min\*1.73m2 ) ≤ eGFR ≤ 59 ml/(min\*1.73m2 )\]; * 11 g/dl ≤ hemoglobin \< 13 g/dl in men and 11 g/dl ≤ hemoglobin \< 12 g/dl in women; - spontaneous bleeding requiring hospitalization or blood transfusion in the past 6 months to 12 months; * long-term use of oral NSAIDs or steroids * Ischemic stroke of any duration not covered by the primary criteria. Exclusion Criteria: * Patients who were already bleeding at the time of baseline inclusion * Patients who could not be followed up (including previously reserved phone changes, etc.) to obtain MACE events.