Clinical Research Directory
Browse clinical research sites, groups, and studies.
Lesion Composition and Quantitative Imaging Analysis on Breast Cancer Diagnosis
Sponsor: University of Hawaii
Summary
The objective is to better identify suspicious breast lesions that need to be biopsied for malignancy in women currently recommended for biopsy. The long-term goal is to reduce unnecessary biopsies and increase biopsy yield. To do this, the investigators have developed an innovative way to use FDA-approved breast imaging protocols to acquire multispectral images to measure the composition of suspicious breast lesions. The central hypothesis is that breast tissue composition in combination with analysis of morphological and textural tissue characteristics on digital breast tomosynthesis (DBT) imaging will yield significantly higher breast cancer specificity than conventional interpretation of DBT alone.
Key Details
Gender
FEMALE
Age Range
20 Years - 85 Years
Study Type
OBSERVATIONAL
Enrollment
600
Start Date
2022-08-01
Completion Date
2026-07
Last Updated
2023-02-02
Healthy Volunteers
No
Conditions
Interventions
q3CB
The q3CB/ncCEM/DBT acquisition protocol consists of a combination of DBT volume reconstructions and projection dual-energy mammograms acquired with a clinical contrast enhanced mammography (CEM) protocol, without contrast administration agent.
Locations (3)
H. Lee Moffitt Cancer Center & Research Institute, Inc.
Tampa, Florida, United States
Hawaii Radiology Associates, LTD (East Hawaii Women's Imaging Center)
Hilo, Hawaii, United States
The Queen's Medical Center
Honolulu, Hawaii, United States