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Polymorphism of ITGA4 Gene in Chronic Lymphocytic Leukemia
Sponsor: Sohag University
Summary
Chronic lymphocytic leukemia (CLL) is a clonal lymphoproliferative disorder that is characterized by heterogeneous presentation at the clinical and molecular levels. ITGA4 protein has been found to be deregulated in CLL with adverse clinical outcome. ITGA4 gene (CD49d) encodes a member of the integrin alpha chain family of proteins and is considered a negative prognosticator in CLL with aggressive course and short time to treatment. The aim of the study: is to investigate ITGA4 gene expression pattern in CLL.
Official title: Polymorphism of the ITGA4 Gene (Integrin Subunit Alpha 4) in Chronic Lymphocytic Leukemia
Key Details
Gender
All
Age Range
Any - Any
Study Type
OBSERVATIONAL
Enrollment
80
Start Date
2024-07-01
Completion Date
2024-10-01
Last Updated
2024-06-20
Healthy Volunteers
Yes
Conditions
Locations (1)
Sohag university
Sohag, Egypt