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Cardiometabolic Screening Program
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Summary
This research study is being done to implement a screening program for prediabetes, diabetes, dyslipidemia and/or hyperlipidemia, and higher risk of cardiovascular disease in breast cancer survivors. This program will also help to direct individuals with risk factors to community and institutional resources for management.
Official title: A Cardiometabolic Screening Program for Breast Cancer Survivors
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
450
Start Date
2022-06-03
Completion Date
2027-06-01
Last Updated
2025-06-24
Healthy Volunteers
No
Conditions
Interventions
Prescreening
Eligible patients (history of early stage breast cancer and at least 3 months from completion of local and systemic therapy at Johns Hopkins, reads and speaks English) complete survey for demographics, smoking status \& questions about cardiovascular disease.
Screening and Enrollment
Consent
Baseline
Behavioral Battery and Patient Reported Outcome Quality of Life questionnaires (EORTC QLQ-C30 and QLQ-BR23) Labs (Hba1c + lipid panel if not done within 12 months or if abnormal within 1 year) Abstract vitals from chart review
Interpret BMI
Refer to Healthful Eating, Activity and Weight Program (HEAWP) if BMI ≥25 and not already on lifestyle intervention
Interpret HbA1c
HbA1c results categorized as follows: HbA1c \<5.7%; HbA1c 5.7-6.4%; HbA1c 6.5%+; or Known diabetic on medication
Interpret lipid panel and assess other risk factors
Based on above categories: HbA1c \<5.7%: Any of these cardiovascular disease risk factors: current/former tobacco use, total cholesterol \>200, family history of Coronary Artery Disease/Heart Attack in first degree family \<55 year old male or \<65 year old female, systolic blood pressure \>130 HbA1c 5.7-6.4%: Refer to Primary Care Provider and consider Healthful Eating, Activity and Weight Program (HEAWP) HbA1c 6.5%+: Refer to Endocrinology if HbA1c ≥8% Known diabetic on medication: Refer to Endocrinology if HbA1c ≥7%
Assess 10 year risk of cardiovascular event
If risk factors are present - refer to Cardiovascular Disease Prevention Program
Recommendations
Provide individual patient handout based on all above interventions
Follow-Up
6 and 12 month labs (if prior abnormal) and Patient Reported Outcome questionnaires
Locations (1)
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Baltimore, Maryland, United States