Clinical Research Directory

Inclusion Criteria: Patients are eligible for the study if all of the following apply: * Are aged 35 years or above * Have baseline CT study with at least one incidentally detected solid or part-solid (must have a solid component \>=80%) pulmonary nodule that: * is not fully calcified * Is 5-30mm inclusive in maximum axial diameter for the whole lesion measured using manual electronic callipers * Have baseline CT study that includes at least one series that meets all of the following (training for this will be provided): * Is of a type that meets VNC instructions for use * Comprises at least one full-inspiration breath-hold scans without a high degree of contrast media and does not exhibit quality issues (e.g., motion artefacts) Exclusion Criteria: Patients will be excluded from the study if any of the following apply: * Have received a diagnosis for cancer in the last 5 years * Have thoracic implants that impact the image appearance of the nodule * Have more than five reported pulmonary nodules of any size or type excluding fully calcified nodules (this criterion is used as a proxy due to the risk of being an infection or metastasis) * Have one or more additional nodules where any of the following applies: * Are already undergoing follow-up according to pulmonary nodule management standard care * Pure ground glass opacity (GGO) of \>=5mm in maximum axial diameter for the whole lesion measured using manual electronic callipers * \>30mm in maximum axial diameter for the whole lesion measured using manual electronic callipers