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Cannabis' Impact on Alcohol Consumption
Sponsor: Brown University
Summary
This study employs a repeated measures experimental design to examine the effect of THC-dominant dose of cannabis and CBD-dominant dose of cannabis, relative to placebo, on subsequent drinking in an alcohol choice task in which participants choose either to drink or receive monetary reinforcement for drinks not consumed. Cannabis will be administered simultaneously with an alcohol-priming dose or alcohol placebo. The study will enroll up to 350 nontreatment-seeking heavy episodic alcohol drinkers who use cannabis weekly.
Official title: Cannabis' Impact on Alcohol Consumption: Integrating Laboratory and Ecological Momentary Assessment Methods
Key Details
Gender
All
Age Range
21 Years - 50 Years
Study Type
INTERVENTIONAL
Enrollment
350
Start Date
2023-03-16
Completion Date
2027-03-31
Last Updated
2024-08-06
Healthy Volunteers
Yes
Interventions
THC-dominant cannabis
Smoked cannabis with 9.53% THC and 0.09% CBD
CBD-dominant cannabis
Smoked cannabis with 0.35% THC and 11.27% CBD
Cannabis placebo
Smoked placebo cannabis plant material
Alcohol
Drink containing 0.3 g/kg of alcohol
Alcohol placebo
Placebo beverage contains only juice and a negligible trace of alcohol for masking
Locations (1)
Brown University
Providence, Rhode Island, United States