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Mechanisms of Disease R/R in CAR-T for Hematologic Malignancies
Sponsor: Duke University
Summary
The primary purpose of this IRB protocol is to perform immune profiling focusing on the measurement of Myeloid derived suppressor cells (MDSCs) over time in patients receiving Chimeric antigen receptor (CAR) T therapy and determine the correlation between immune profile and disease relapse/resistance in CAR T therapy.
Official title: Mechanisms of Disease Relapse/Resistance in CAR T Therapy for Hematologic Malignancies
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
50
Start Date
2022-05-27
Completion Date
2026-11-01
Last Updated
2025-09-02
Healthy Volunteers
Not specified
Conditions
Interventions
Blood draw
Patients will provide a blood draw for research and repository
Locations (1)
Duke University
Durham, North Carolina, United States