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RECRUITING
NCT05397197
NA

Impact of Moderate Preterm Birth on Vocabulary Acquisition

Sponsor: Assistance Publique Hopitaux De Marseille

View on ClinicalTrials.gov

Summary

Children born prematurely may present a neurodevelopmental disorder with a language delay diagnosed as early as 2-3 years of age. This situation is not uncommon: each year in France, approximately 35,000 children are born between 32 and 36 weeks of amenorrhea. In our most recent work, we have shown that moderate premature infants show an attenuated cortical response to a vowel change, suggesting a deficit in the cortical encoding of vowels. This work needs to be continued in order to better understand syllable encoding and identify the neuroplasticity mechanisms underlying early speech encoding. The identification of markers to predict language development is essential for the screening of these children at risk of language delay. These children could thus benefit from early adapted care even before the appearance of language deficits.

Official title: A Longitudinal Study of the Impact of Moderate Preterm Birth on Cortical and Subcortical Processing of Speech Sounds and Vocabulary Acquisition

Key Details

Gender

All

Age Range

0 Days - 2 Years

Study Type

INTERVENTIONAL

Enrollment

160

Start Date

2022-10-19

Completion Date

2030-10-19

Last Updated

2026-01-08

Healthy Volunteers

Yes

Conditions

Interventions

OTHER

Electroencephalography

experimental task, neuropsychological evaluation, clinical exam

Locations (1)

Service de Neuropédiatrie

Marseille, France