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RECRUITING
NCT05397262
NA

Organ-preservative Therapy of Bladder Cancer With Radiotherapy or Radiochemotherapy Combined With Hyperthermia

Sponsor: University of Erlangen-Nürnberg Medical School

View on ClinicalTrials.gov

Summary

Analysis of the efficacy and the compatibility of deep regional hyperthermia in combination with radiotherapy and chemoradiotherapy in bladder cancer

Official title: Register-Trial Based on an Agreement of Health Insurances With the Department of Radiation Therapy of the University Hospital Erlangen for the Application of Regional Hyperthermia in Bladder Cancer: Organ-preservative Therapy of Bladder Cancer With Radiotherapy or Radiochemotherapy Combined With Hyperthermia

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

1000

Start Date

2017-03-29

Completion Date

2099-12-31

Last Updated

2024-05-09

Healthy Volunteers

No

Conditions

Interventions

OTHER

Hyperthermia

Deep Regional Hyperthermia (RHT) 1-2/week up to 10 sessions a type of cancer treatment in which body tissue is exposed to high temperatures (up to 113°F).

RADIATION

Radiotherapy

50,4 Gy (28 x 1,8 Gy) plus Boost: If R0: 5,4 Gy; If R1/2: 9 Gy

DRUG

Chemotherapy 5-Fluorouracil

600 mg/m\^2 civ 120h; d 1-5, 29-33

DRUG

Chemotherapy Cisplatin

20 mg/m\^2; d1-5, 29-33

Locations (1)

Dept. of Radiation Therapy, University Hospital Erlangen

Erlangen, Germany