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RECRUITING
NCT05398302
PHASE1

Image-Guided Biopsies to Identify Mechanisms of Resistance in Patients With Metastatic Castration Resistant Prostate Cancer Treated With 177Lu-PSMA Radioligand Therapy

Sponsor: Jonsson Comprehensive Cancer Center

View on ClinicalTrials.gov

Summary

This clinical trial studies mechanisms of resistance to 177-lutetium prostate specific membrane antigen (177Lu-PSMA) radioligand therapy using image-guided biopsies in patients with castrate-resistant prostate cancer that had spread to other places in the body (metastatic). Diagnostic procedures, such as image guided biopsies, may help in learning how well 177Lu-PSMA works to kill tumor cells and allow doctors to plan better treatment.

Official title: Radiologically Guided Biopsies of Metastatic Castration Resistant Prostate Cancer to Identify Mechanisms of Resistance in Patients Undergoing 177Lu-PSMA Radioligand Therapy

Key Details

Gender

MALE

Age Range

Any - Any

Study Type

INTERVENTIONAL

Enrollment

30

Start Date

2024-04-26

Completion Date

2027-12-31

Last Updated

2026-03-30

Healthy Volunteers

No

Interventions

PROCEDURE

Image Guided Biopsy

Undergo image-guided biopsy

Locations (1)

UCLA / Jonsson Comprehensive Cancer Center

Los Angeles, California, United States