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RECRUITING
NCT05401292
PHASE4

Skin Preparation for Elective Foot and Ankle Surgery

Sponsor: University of Missouri-Columbia

View on ClinicalTrials.gov

Summary

Surgical site infections (SSIs) make about 31% of all nosocomial infections and they are the most common hospital-acquired infection. For foot and ankle elective interventions, SSI rate is reported between 0.4% and 3.6%. This study will investigate the effectiveness of skin cleaning with isopropyl alcohol and scrubbing with chlorhexidine soap before standard skin preparation in reducing microbial load and surgical site infections for elective foot and ankle surgeries. Current standard of care includes skin preparation with iodine or chlorhexidine solution prior to sterile draping and the start of surgery. Standard of care will be applied to all patients. The use of an additional "pre-scrub" with isopropyl alcohol and scrubbing with chlorhexidine soap will be applied to the experimental group. The control group will receive only the standard of care skin preparation with iodine or chlorhexidine solution prior to draping.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

100

Start Date

2022-02-15

Completion Date

2025-12

Last Updated

2025-04-25

Healthy Volunteers

No

Interventions

DRUG

Hibiclens

antiseptic/antimicrobial skin cleanser for skin wound and general skin cleansing

DRUG

Isopropyl Alcohol 70% Topical Application Solution

First aid antiseptic

Locations (1)

University of Missouri

Columbia, Missouri, United States