Clinical Research Directory
Browse clinical research sites, groups, and studies.
Screening of Malignant Hyperthermia Susceptible Individuals
Sponsor: Peking University Third Hospital
Summary
This study intends to target patients who underwent surgery under general anesthesia during the study period and developed malignant hyperthermia during or after surgery. Therefore, the total sample size was estimated to be about 50 people based on the past incidence of this rare disease. Every year, about 20 patients and their families who developed malignant hyperthermia during or after surgery will participate in this nationwide study (estimated by the current incidence of malignant hyperthermia), and about 1-5 patients will be admitted to Peking University Third Hospital participate in this research. Relevant specimens were collected from malignant hyperthermia (MH) patients and their family members for genetic analysis to determine the mutation of MH-related pathogenic gene loci.
Official title: Molecular Genetics Study on Screening of Malignant Hyperthermia Susceptible Individuals
Key Details
Gender
All
Age Range
0 Years - 100 Years
Study Type
OBSERVATIONAL
Enrollment
50
Start Date
2022-02-22
Completion Date
2041-02
Last Updated
2022-06-02
Healthy Volunteers
No
Conditions
Locations (1)
Peking University Third Hospital
Beijing, Beijing Municipality, China