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Study of the Biological Function of Muscle Satellite Cells From Patients With Obstetric Brachial Plexus Palsy
Sponsor: University Hospital, Montpellier
Summary
The purpose of this prospective work is to study the consequences of obstetrical brachial plexus paralysis on the rotator muscles of the shoulder. The hypothesis is that shoulder stiffness of these children is due to an impairment of the shoulder rotator muscles. The investigators want to test the regenerative capacities of these muscles. The development of a cellular model of this pathology will allow to test new therapeutic perspectives and to validate our hypothesis.
Official title: Study of the Biological Function of Muscle Satellite Cells From Patients With Obstetric Brachial Plexus Palsy Satellite Cell Obstetrical PlExus (SCOPE)
Key Details
Gender
All
Age Range
2 Years - 15 Years
Study Type
INTERVENTIONAL
Enrollment
8
Start Date
2022-10-17
Completion Date
2025-06-25
Last Updated
2026-06-18
Healthy Volunteers
No
Conditions
Interventions
Muscle biopsy
Peroperative muscle biopsy will be performed during a planned shoulder surgery (arthrolysis and/or muscle transfer)
Locations (1)
Chu Montpellier
Montpellier, France