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RECRUITING
NCT05404256
NA

Comparison of Effectiveness of TissuePatchTM in Preventing Postoperative Pancreatic Fistula

Sponsor: Xijing Hospital of Digestive Diseases

View on ClinicalTrials.gov

Summary

Postoperative pancreatic fistula is one of the most serious complications after gastric cancer surgery and can lead to surgery-related death. Postoperative pancreatic fistula for gastric cancer often occurs in accidental injury of pancreas during peripancreatic lymph node dissection, blunt separation of pancreatic capsule injury, laparoscopic instrument clamp and long-term compression of pancreas, etc. TissePatchTM is a synthetic, self-adhesive, absorbable surgical sealant and barrier used to seal and reinforce wounds and prevent leakage of air, blood, and fluid during neurosurgery, spine, chest, and soft tissue surgery. Therefore, we proposed whether the use of TissuePatchTM can reduce the occurrence of pancreatic fistula after gastric cancer surgery, and the clinical trial of the effectiveness of TissuePatchTM on the prevention of pancreatic fistula after radical gastrectomy of gastric cancer can provide new clinical data for the prevention of pancreatic fistula after gastric cancer surgery, and help reduce a series of adverse reactions caused by pancreatic fistula in patients.

Official title: Randomized Controlled Trial for Comparison of the Effects of Preventing Postoperative Pancreatic Fistula by With Versus Without TissuePatchTM Cover the Wound Surface of Pancreatic Capsule

Key Details

Gender

All

Age Range

18 Years - 75 Years

Study Type

INTERVENTIONAL

Enrollment

154

Start Date

2022-08-01

Completion Date

2026-04-01

Last Updated

2024-05-08

Healthy Volunteers

No

Interventions

OTHER

Radical gastrectomy +D2 lymphadenectomy+TissuePatchTM to seal pancreatic tissue surface

Radical gastrectomy +D2 lymphadenectomy+TissuePatchTM to seal pancreatic tissue surface

OTHER

Radical gastrectomy +D2 lymphadenectomy

Radical gastrectomy +D2 lymphadenectomy

Locations (1)

Xijing Hospital of Digestive Disease

Xi'an, Shaanxi, China