Clinical Research Directory

Inclusion Criteria: * Adult patient, male or female, eligible for dental extraction under local anesthesia, * either a tooth on the arch, * either wisdom tooth(s) (2 homolateral wisdom teeth (maxilla + mandibular) or a mandibular wisdom tooth). * Fluent in speaking and reading French. * Able to give informed consent to research. * Affiliation to a Social Security scheme. Exclusion Criteria: * Pregnant or breastfeeding women. * Contraindication to paracetamol, NSAIDs, tramadol, or anesthetic agents local. * Patient uncooperative, unlikely or unable to comply with all procedures of the protocol. * Chronic use of opiates, in a therapeutic or illicit context. * Chronic depression on long-term antidepressants. * Stomatological pathology that may interfere with the conduct of the intervention or modify the results: insufficient mouth opening, pathologies of the temporal mandibular joints ... * Active medical pathology, or any medical condition judged by the investigator to be incompatible with the study. * Patient under guardianship, curatorship or safeguard of justice. * Refusal to participate.