Clinical Research Directory

Inclusion Criteria: * Able to comprehend and be willing to sign an informed consent form (ICF). * Diagnosis of local, loco-regionally advanced, or metastatic malignancy for whom radiotherapy is indicated * Radiotherapy to be delivered on the RMRS X1 with IMRT, SBRT, or BgRT technique. * Absence of concurrent illness that deems radiotherapy a contraindication which will be determined by the treating radiation oncologist. * Female and male patients of child-bearing potential willing to take appropriate precautions to avoid pregnancy while being treated. Permitted methods in preventing pregnancy should be communicated to the patient and their understanding confirmed by the treating Physician. * For BgRT patients only: Deemed eligible for BgRT with FDG per BgRT planning session Exclusion Criteria: * Pregnant or expecting to conceive during the study. * Has a known psychiatric or substance abuse disorder that would interfere with the participant's ability to cooperate with study requirements and follow-up visits. * Inability to maintain immobilization, supine position for planning and treatments. * For BgRT patients only: Known allergy to FDG