Clinical Research Directory

Inclusion Criteria: * Aged 18-45 years old; * Breast pain starts within 2 weeks before menses, and improves after onset, dull, heavy, or aching, bilateral, poorly localized, and extends into the axilla ; * Fulfilling all conditions mentioned below: a. Moderate or severe breast pain as indicating 3 or more on scale of 1-10 on the VAS;b. History of CM for at least the past three consecutive cycles;c. Days of premenstrual breast pain≥3 days and≤14 days; d.A history of regular menstrual cycles of 28 plus/minus 3 days; * Breast X-ray or breast ultrasound examination is excluded from malignant breast lesions; * The patient signed the informed consent and voluntarily participated in the study. Exclusion Criteria: * Accepted acupuncture or drugs to treat breast pain within 1 month before entering the study; * With breast inflammation, breast fibroma, breast cystic hyperplasia, and other benign breast lesions； * With severe primary diseases in the cardiovascular system, pulmonary system, liver, kidney, and hematopoietic system; * History of breast cancer among first-degree relatives; * Breast pain caused by Costochondritis, chest wall injury, rib fracture, and other extramammary pain diseases; * The patient is pregnant or lactating; * with serious mental illness; * Poor compliance; * Patient has participated in other clinical trials within 1 month; * with serious skin disease or infection at the acupuncture site.