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ENROLLING BY INVITATION
NCT05411549
NA

The Role of a Mediterranean Diet in Patients With Endometriosis: a Feasibility Trial

Sponsor: McMaster University

View on ClinicalTrials.gov

Summary

This study aims to test if making changes to diet can affect the pelvic pain associated with endometriosis. One group will follow a Mediterranean diet for 12 weeks while the control group will continue with their current diet. We will be looking at the feasibility of a larger-scale trial as well as self-reported quality of life and self-reported pain using standardized questionnaires, that have previously been used and validated, and assessing how this diet affects biomarkers associated with endometriosis and inflammation. Further, we will test how this change in diet affects the gut microbe flora.

Official title: The Role of a Mediterranean Diet in Long-term Management of Pelvic Pain in Patients With Endometriosis: a Feasibility Trial

Key Details

Gender

FEMALE

Age Range

18 Years - 45 Years

Study Type

INTERVENTIONAL

Enrollment

24

Start Date

2023-08-22

Completion Date

2026-06

Last Updated

2025-05-09

Healthy Volunteers

No

Conditions

Interventions

BEHAVIORAL

Diet Modification to Adopt Mediterranean Diet

Participants enrolled in group 1 will be counselled by a dietician and asked to adopt a Mediterranean diet for a 12-week period from counselling. Participants will complete a series of Mediterranean Diet Adherence Score, pain questionnaires as well as quality of life questionnaires (EPH-30, SF-36, GIQLI) which have been previously validated. Participants in this group will give a baseline and final visit blood sample and stool samples to assess inflammation biomarkers as well as gut microflora.

Locations (1)

McMaster University

Hamilton, Ontario, Canada