Clinical Research Directory
Browse clinical research sites, groups, and studies.
Oxidative Lipidomic Biomarkers During Mechanical Ventilation in Critically Ill Patients (OXY-BAL).
Sponsor: Ohio State University
Summary
The aim of this study is to identify and determine the levels of oxidized lipids and lipid mediators following exposure to oxygen supplementation during mechanical ventilation by oxidative lipidomics. The investigators will include patients with mechanical ventilation and have received FiO2=\>0.5 atleast 90 minutes and collected two sequential mini bronchoalveolar lavage on them 24 hours apart. Mass Spectrometry Lipid chromatography will be conducted and clinical data will be analyzed.
Key Details
Gender
All
Age Range
18 Years - 110 Years
Study Type
OBSERVATIONAL
Enrollment
200
Start Date
2023-03-01
Completion Date
2026-09-01
Last Updated
2024-04-26
Healthy Volunteers
No
Interventions
oxygen
oxygen exposure of more than 50% for 1.5 hours
Locations (1)
Ohio State University Medical Center
Columbus, Ohio, United States