Clinical Research Directory
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Study of ARO-APOC3 in Adults With Dyslipidemia
Sponsor: Arrowhead Pharmaceuticals
Summary
This is an open-label extension of the parent studies AROAPOC3-2001 and AROAPOC3-2002. Adult participants with dyslipidemia who completed the blinded 12-month period from either parent study and continued to meet eligibility criteria had the option to be enrolled into this study. Eligible enrolled participants initially received open-label ARO-APOC3 every three or six months at the assigned dose level of the parent study until a final dose of 25 mg was selected, at which point all participants transitioned to the selected dosing regimen of 25 mg every 3 months.
Official title: A Phase 2 Open-Label Extension Study to Evaluate the Long-Term Safety and Efficacy of ARO-APOC3 in Adults With Dyslipidemia
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
418
Start Date
2022-07-07
Completion Date
2025-09-22
Last Updated
2026-05-12
Healthy Volunteers
No
Conditions
Interventions
ARO-APOC3
ARO-APOC3 Injection
Locations (60)
Clinical Research Site 1
Beverly Hills, California, United States
Clinical Research Site 2
Northridge, California, United States
Clinical Research Site 3
Palm Springs, California, United States
Clincal Research Site 4
Boca Raton, Florida, United States
Clinical Research Site 5
Fort Lauderdale, Florida, United States
Clinical Research Site 8
Miami, Florida, United States
Clinical Research Site 6
Miami, Florida, United States
Clinical Research Site 9
Miami Springs, Florida, United States
Clinical Research Site 10
Pembroke Pines, Florida, United States
Clinical Research Site 11
Port Orange, Florida, United States
Clinical Research Site 12
Dunwoody, Georgia, United States
Clinical Research Site 13
Minneapolis, Minnesota, United States
Clinical Research Site 14
Tupelo, Mississippi, United States
Clinical Research Site 15
Omaha, Nebraska, United States
Clinical Research Site 16
Las Vegas, Nevada, United States
Clinical Research Site 17
Long Island City, New York, United States
Clinical Research Site 18
New Windsor, New York, United States
Clinical Research Site 19
New York, New York, United States
Clinical Research Site 20
Morehead City, North Carolina, United States
Clinical Research Site 21
Fargo, North Dakota, United States
Clinical Research Site 22
Marion, Ohio, United States
Clinical Research Site 23
Maumee, Ohio, United States
Clinical Research Site 24
Oklahoma City, Oklahoma, United States
Clinical Research Site 25
Greenville, South Carolina, United States
Clinical Research Site 26
Chattanooga, Tennessee, United States
Clinical Research Site 29
Houston, Texas, United States
Clinical Research Site 27
Houston, Texas, United States
Clinical Research Site 28
Houston, Texas, United States
Clinical Research Site 30
San Antonio, Texas, United States
Clinical Research Site 31
Manassas, Virginia, United States
Clinical Research Site 32
Camperdown, New South Wales, Australia
Clinical Research Site 33
Milton, Queensland, Australia
Clinical Research Site 34
Sippy Downs, Queensland, Australia
Clinical Research Site 35
Adelaide, South Australia, Australia
Clinical Research Site 36
Clayton, Victoria, Australia
Clinical Research Site 37
Joondalup, Washington, Australia
Clinical Research Site 38
Nedlands, Washington, Australia
Clinical Research Site 39
Concord, Ontario, Canada
Clinical Research Site 40
London, Ontario, Canada
Clinical Research Site 41
Chicoutimi, Quebec, Canada
Clinical Research Site 43
Montreal, Quebec, Canada
Clinical Research Site 44
Québec, Quebec, Canada
Clinical Research Site 46
Balatonfüred, Hungary
Clinical Research Site 47
Békéscsaba, Hungary
Clinical Research Site 48
Debrecen, Hungary
Clinical Research Site 49
Gyöngyös, Hungary
Clinical Research Site 50
Komárom, Hungary
Clinical Research Site 51
Nyíregyháza, Hungary
Clinical Research Site 53
Amsterdam, Netherlands
Clinical Research Site 54
Sneek, Netherlands
Clinical Research Site 55
Zwijndrecht, Netherlands
Clinical Research Site 58
Papatoetoe, Aukland, New Zealand
Clinical Research Site 56
Christchurch, New Zealand
Clinical Research Site 57
Christchurch, New Zealand
Clinical Research Site 59
Bydgoszcz, Poland
Clinical Research Site 64
Lodz, Poland
Clinical Research Site 63
Lodz, Poland
Clinical Research Site 60
Oświęcim, Poland
Clinical Research Site 61
Poznan, Poland
Clinical Research Site 62
Rzeszów, Poland