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COMPLETED
NCT05415774
NA

Combined Deep Brain Stimulation in Parkinson's Disease

Sponsor: University Hospital, Toulouse

View on ClinicalTrials.gov

Summary

The study is a pilot study on Parkinson's disease patients to evaluate Combined deep brain stimulation of the substantia nigra pars reticulata and of the subthalamic nucleus for unresponsive freezing of gait.

Official title: Combined Deep Brain Stimulation of the Substantia Nigra Pars Reticulata and of the Subthalamic Nucleus for Unresponsive Freezing of Gait in Parkinson's Disease: a Pilot Cross-over Study

Key Details

Gender

All

Age Range

18 Years - 100 Years

Study Type

INTERVENTIONAL

Enrollment

10

Start Date

2022-09-09

Completion Date

2023-05-10

Last Updated

2026-05-06

Healthy Volunteers

No

Interventions

DEVICE

1 : S-C1-C2

Deep brain stimulation of the substantia nigra pars reticulata and of the subthalamic nucleus according to the order of randomisation (see intervention name) : * Standard stimulation * 125Hz at both STN and SNr for C1, * 125Hz for STN and 60 for SNr for C2

DEVICE

2 : S-C2-C1

Deep brain stimulation of the substantia nigra pars reticulata and of the subthalamic nucleus according to the order of randomisation (see intervention name) : * Standard stimulation * 125Hz at both STN and SNr for C1, * 125Hz for STN and 60 for SNr for C2

DEVICE

3 : C1 - S - C2

Deep brain stimulation of the substantia nigra pars reticulata and of the subthalamic nucleus according to the order of randomisation (see intervention name) : * Standard stimulation * 125Hz at both STN and SNr for C1, * 125Hz for STN and 60 for SNr for C2

DEVICE

4 : C1 -C2 - S

Deep brain stimulation of the substantia nigra pars reticulata and of the subthalamic nucleus according to the order of randomisation (see intervention name) : * Standard stimulation * 125Hz at both STN and SNr for C1, * 125Hz for STN and 60 for SNr for C2

DEVICE

5 : C2 - S - C1

Deep brain stimulation of the substantia nigra pars reticulata and of the subthalamic nucleus according to the order of randomisation (see intervention name) : * Standard stimulation * 125Hz at both STN and SNr for C1, * 125Hz for STN and 60 for SNr for C2

DEVICE

6 : C2 - C1 - S

Deep brain stimulation of the substantia nigra pars reticulata and of the subthalamic nucleus according to the order of randomisation (see intervention name) : * Standard stimulation * 125Hz at both STN and SNr for C1, * 125Hz for STN and 60 for SNr for C2

Locations (1)

Uh Toulouse

Toulouse, France