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Understanding How Methadone Treatment During Surgery Affects Pain Levels and the Need for Pain Medications After Surgery
Sponsor: Memorial Sloan Kettering Cancer Center
Summary
The researchers are doing this study to find out whether giving methadone during spinal surgery helps manage pain in the first 72 hours after surgery better than other standard pain medications. Participants' pain will be measured by how much pain is reported after surgery, and how much additional pain medication is needed to lower pain levels. The researchers will look at whether giving methadone during surgery reduces the need for other pain medications after surgery. In addition, the team will compare the effects of the two standard treatments- one with methadone and one without methadone to to evaluate which one works best.
Official title: Modulation of Post-operative Opioid Consumption and Pain by Intraoperative Methadone for Cancer Related Spinal Surgery - An Investigator Initiated Trial (IIT), Cluster Randomization Trial
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
17
Start Date
2022-06-06
Completion Date
2027-06
Last Updated
2026-01-27
Healthy Volunteers
No
Conditions
Interventions
Methadone
methadone 0.2 mg/kg IV.
Locations (1)
Memorial Sloan Kettering Cancer Center (All Protocol Activities)
New York, New York, United States