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Loratadine for the Prevention of G-CSF-related Bone Pain
Sponsor: AHS Cancer Control Alberta
Summary
The research question for the current study is: Is loratadine more effective than placebo in preventing G-CSF-related bone pain during autologous hematopoetic stem cell transplant in patients with lymphoma or multiple myeloma? The hypothesis is that prophylaxis with loratadine will help prevent or reduce the severity of bone pain in this setting.
Official title: Loratadine for the Prevention of Bone Pain Caused by Granulocyte Colony Stimulating Factor (G-CSF) During Stem Cell Mobilization
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
78
Start Date
2024-11-28
Completion Date
2026-12-01
Last Updated
2026-02-05
Healthy Volunteers
No
Conditions
Interventions
Loratadine
Loratadine is 2nd generation inverse agonist that exerts its effect by targeting H1 histamine receptors.
Placebo
Placebo sugar pill
Locations (1)
Cross Cancer Institute
Edmonton, Alberta, Canada