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RECRUITING
NCT05424406
NA

Role of Sleep Reactivity in Shift Work Disorder

Sponsor: Henry Ford Health System

View on ClinicalTrials.gov

Summary

The purpose of this project is to test sleep reactivity as an independent cause of Shift Work Disorder (SWD). The primary hypothesis is that those with high sleep reactivity will show persistent SWD symptoms after experimental reduction of circadian misalignment, which will then be mitigated with CBT.

Official title: Sleep Reactivity as a Novel Mechanism in Shift Work Disorder

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

150

Start Date

2023-01-01

Completion Date

2027-10-01

Last Updated

2025-10-14

Healthy Volunteers

No

Interventions

BEHAVIORAL

Active phototherapy

Timed bright light exposure delivered in a controlled laboratory setting (10,000 photopic lux) designed to delay the DLMO to 4 am or later.

BEHAVIORAL

Control phototherapy

Timed less intense light exposure delivered in a controlled laboratory setting (100 photopic lux) that still has a perceptible alerting effect but is not designed to shift circadian phase.

BEHAVIORAL

Cognitive Behavioral Therapy (CBT)

Cognitive strategies will identify stressors (e.g., dysfunctional beliefs about sleep) and intervene on worry and rumination with cognitive reappraisal and active coping. Sessions will be conducted by a trained behavioral sleep medicine provider via telemedicine to increase accessibility.

BEHAVIORAL

Sleep education control

Sleep duration recommendations will be equivalent to the CBT group (8 hours of sleep opportunity) to ensure that outcomes are not confounded by time in bed. Materials in the sleep education control condition will be separated into weekly electronic materials monitored for engagement and completion.

Locations (1)

Henry Ford Columbus Medical Center

Novi, Michigan, United States