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Correlation Between Perioperative Autonomic Function and Post-induction Hypotension in Elderly Patients
Sponsor: Peking Union Medical College Hospital
Summary
Elderly patients have a higher risk of post-induction hypotension (PIH). The decreased cardiovascular autonomic function at baseline in elderly patients may contribute to the development of PIH. The objective of our study is to effect of preoperative cardiovascular autonomic modulation in PIH, we will recruit elderly patients who are going to have general anesthesia surgery and measure preoperative baroreflex sensitivity (BRS) and heart rate variability (HRV). The primary outcome will be PIH. Secondary outcomes included: early intraoperative hypotension, postoperative complications, and 30-day postoperative mortality.
Official title: Correlation Between Perioperative Autonomic Function and Adverse Events Such as Post-induction Hypotension in Elderly Patients
Key Details
Gender
All
Age Range
65 Years - 100 Years
Study Type
OBSERVATIONAL
Enrollment
180
Start Date
2022-07-25
Completion Date
2025-03-01
Last Updated
2024-04-19
Healthy Volunteers
No
Conditions
Interventions
Perioperative autonomic function assessment
Patients will have BRS and HRV measurements taken for approximately 20 minutes, one day before surgery and on the day of surgery. We use LiDCO rapid to conduct non-invasive pulse and beat-to-beat blood pressure monitoring.
Locations (1)
Peking Union Medical College Hospital
Beijing, China