Clinical Research Directory

Inclusion Criteria: * Diagnosis of a chronic, non-terminal pain condition (pain most days for at least 6 months) * Average pain intensity and interference with enjoyment of life and/or general activity rated \> 4/10 over the past week, as measured by the PEG * Meet clinical criteria for major depression via DSM5 criteria, as assessed by the Mini International Neuropsychiatric Interview (MINI) Exclusion Criteria: * Serious or unstable medical illness (e.g., cardiovascular disease) * Lifetime history of psychotic disorder, bipolar disorder, obsessive-compulsive disorder * Active substance abuse or psychosocial instability (e.g., homelessness) that could compromise study participation * Changes to professionally delivered pain or mood treatment (e.g., no discontinuation of a treatment; no increasing the dose of medication) one month preceding the baseline assessment * Significant neurologic disorder, increased risk of seizure for any reason or family/personal history of seizure * Contraindications to rTMS treatment as outlined by the Safety of TMS Consensus group, which includes implanted metallic objects above the neck, implanted electrical devices (pacemakers/spinal cord stimulators), and pregnancy * Prior trial of rTMS for any condition and/or lack of responsiveness to electroconvulsive therapy