Clinical Research Directory
Browse clinical research sites, groups, and studies.
Assessment the Cancer Risk of Indeterminate Thyroid Nodules Through Integration of Clinical, Ultrasonographic and Multiomic Features
Sponsor: University of Cagliari
Summary
Indeterminate thyroid nodules have a mild risk of malignancy (15-30%). The aim of our study is to individuate new biomarkers of thyroid carcinoma through multiomic analyses of blood samples and of specimen samples of patients with indeterminate thyroid nodules.
Official title: A Novel, Multimodal, Machine-learning Grounded Approach to Assess the Oncological Risk of Indeterminate Thyroid Nodules
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
256
Start Date
2023-01-01
Completion Date
2027-12-31
Last Updated
2022-06-23
Healthy Volunteers
No
Conditions
Interventions
Multiomic analyses of blood and surgical specimens
The following items will be evaluated: * cell free dna length and integrity * presence or absence of SNPs in cfDNA and in DNA extracted from surgical samples * qualitative and quantitative evaluation of serum and surgical specimens proteome (proteomics)
Locations (1)
AOU Cagliari
Cagliari, CA, Italy