Clinical Research Directory
Browse clinical research sites, groups, and studies.
Validation of SMS Protocol for HCC Screening in High-risk Patients
Sponsor: Erasmus Medical Center
Summary
The investigators will assess implementation of the proposed SMS protocol as a surveillance tool in patients at high risk of developing HCC in a prospective multicenter study.
Official title: Validation of a Short and Effective MRI Surveillance (SMS) Protocol for Hepatocellular Carcinoma Screening in Practice
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
470
Start Date
2023-11-07
Completion Date
2026-06-01
Last Updated
2023-11-29
Healthy Volunteers
Not specified
Conditions
Interventions
Short MRI surveillance (SMS) protocol
Bi-annual, non-contrast agents, MRI screening consisting of Diffusion Weighted Imaging (b-values of 50 and 800 s/mm2), T2-weighted imaging and T1-weighted in- and out-of-phase imaging
Bi-annual ultrasonography screening
Bi-annual ultrasonography for screening of HCC in high-risk patients
Locations (6)
Academic Medical Center
Amsterdam, North Holland, Netherlands
Medisch Spectrum Twente
Enschede, Overijssel, Netherlands
Albert Schweitzer Ziekenhuis
Dordrecht, South Holland, Netherlands
Erasmus Medical Center
Rotterdam, South Holland, Netherlands
St. Franciscus Gasthuis & Vlietland
Rotterdam, South Holland, Netherlands
Maasstad Ziekenhuis
Rotterdam, South Holland, Netherlands