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Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) International Registry
Sponsor: Immune Oncology Research Institute
Summary
Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) is a very rare hematologic malignancy. Despite recent advances, at present there is no consensus on the optimal treatment of BPDCN. The optimal therapy of disease remains to be determined, and due to the rarity of cases, there is a need for international collaboration to collect data on BPDCN clinical presentations, diagnostics, treatment regimens and outcomes. Therefore, the objectives of this study are: (1) to build a large database of patients with BPDCN, (2) to investigate the characteristics and outcome of the disease with different treatment regimens, (3) to evaluate prognostic factors, and (4) to generate data-based prospective treatment recommendations.
Key Details
Gender
All
Age Range
Any - Any
Study Type
OBSERVATIONAL
Enrollment
200
Start Date
2022-07-01
Completion Date
2032-07
Last Updated
2026-02-17
Healthy Volunteers
No
Locations (20)
Sylvester Comprehensive Cancer Center, University of Miami
Miami, Florida, United States
Moffitt Cancer Center
Tampa, Florida, United States
Seattle Children's Cancer and Blood Disorders Center
Seattle, Washington, United States
Hematology Center named after prof. R. Yeolyan
Yerevan, Armenia
University of Calgary
Calgary, Alberta, Canada
Children's Hospital of Eastern Ontario, University of Ottawa
Ottawa, Ontario, Canada
Cyprus Society of Haematology
Nicosia, Cyprus
Oncology Center, Mansoura University Faculty of Medicine
Al Mansurah, Egypt
M. Iashvili Children's Central Hospital
Tbilisi, Georgia
Department of Medical Oncology, Dr. B.R.A Institute Rotary Cancer Hospital, All India Institute of Medical Sciences
New Delhi, India
Pediatric Hematology Oncology, Children's Welfare Teaching Hospital, Medical City, College of Medicine, University of Baghdad
Baghdad, Iraq
University of Perugia - Azienda Ospedaliera Perugia
Perugia, Italy
Department of Biomedicine and Prevention, University of Rome Tor Vergata
Roma, Italy
Department of hematology, Kuwait Cancer Control Center
Kuwait City, Kuwait
Fundeni Clinical Institute, Department of Acute Leukemia
Bucharest, Romania
China Medical University Children's Hospital
Taichung, Taiwan
Turkish Pediatric Cancer Registry
Ankara, Turkey (Türkiye)
Istanbul University, Oncology Institute
Istanbul, Turkey (Türkiye)
University of Health Sciences, Umraniye Research and Education Hospital, Pediatric Hematology and Oncology Department, Pediatric Bone Marrow Transplantation Unit
Istanbul, Turkey (Türkiye)
Broomfield Hospital, Haematology Mid and South Essex University Hospitals Group
Chelmsford, Essex, United Kingdom