Clinical Research Directory

Inclusion Criteria: * Aneurysm aortic group: patients treated for an aneurysm of the ascending thoracic aorta with surgical indication according to the ESC guidelines (2014). * Aortic dissection group: patients treated for type A acute aortic dissection or intramural hematoma of the ascending thoracic aorta in emergency. * Control group: patients operated for aortic valve replacement (little aortic sample before closing aortotomy) or coronary artery bypass grafting which the use of a saphenous graft and the performance of a proximal anastomosis on the ascending aorta is planned Exclusion Criteria: * Patients under 18 years old * Other acute aortic syndromes (penetrating ulcers, iatrogenic or traumatic dissections) * Patients treated for aortic valve replacement in the context of infective endocarditis * Patients treated for emergency aortic valve replacement or coronary bypass surgery\*\* * Pregnant, parturient and breastfeeding women * Patients protected by an administrative or judicial measure (curatorship, guardianship) * Patients receiving psychiatric care under duress * Adults subject to a legal protection measure. * Patients whose the samples planned for the study could not be taken; * Patients in the control group whose tissue sampling will not be performed.