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NCT05435092

Clinical Correlation of TKA Alignment and Native Knee Anatomy

Sponsor: University Hospital, Basel, Switzerland

View on ClinicalTrials.gov

Summary

Total knee arthroplasty (TKA) is still considered the treatment of choice for painful osteoarthritis. In the last decades neutral mechanical knee alignment in the coronal plane has been considered the gold standard. However, the optimal TKA alignment is still debated. Today, component rotation measurements on three-dimensional (3D) reconstructed computed tomography (CT) images are considered the gold standard for assessing native preoperative alignment and TKA component position. In this study pre-and postoperative radiographic measurements, functional scores, and biomechanical parameters of patients with knee osteoarthritis will be assessed with the aim to investigate the relationship between deviations of TKA alignment from native preoperative alignment and clinical, functional and biomechanical alignment.

Official title: Influence of Native Knee Anatomy on Alignment and Outcome After Total Knee Arthroplasty CAT - Clinical Correlation of TKA Alignment and Native Knee Alignment

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

75

Start Date

2022-04-01

Completion Date

2026-10-30

Last Updated

2025-01-31

Healthy Volunteers

Not specified

Interventions

RADIATION

3D-reconstruction CT

Three dimensional CT (3D CT):Method of surface rendition of anatomy by means of a special computer software to capture 3D bone models used to improve the outcomes of Total Knee Arthroplasty (TKA).

Locations (1)

University Hospital Basel

Basel, Canton of Basel-City, Switzerland