Clinical Research Directory

Inclusion Criteria: 1. Age ≥ 18 years; 2. Patients meeting the diagnostic criteria for Rapid rEcurrences of Coronary Unexplained in-stent Restenosis (RECUR); 3. Patients fully informed about the trial procedures who provide written informed consent. Exclusion Criteria: 1. Patients presenting with any of the following: * Other severe comorbidities (e.g., malignant tumors, heart failure) with a life expectancy \<12 months; * Known autoimmune/rheumatic diseases including systemic lupus erythematosus, Takayasu arteritis, Behçet's disease, polyarteritis nodosa, Wegener granulomatosis (granulomatosis with polyangiitis), eosinophilic arteritis, giant cell arteritis, rheumatoid arthritis, or IgG4-related disease; * Variant angina (Prinzmetal's angina); * Coronary artery dissection; * Thrombophilia; * Stent underexpansion. 2. Presence of psychiatric disorders; 3. Known inability to complete expected study follow-up for any reason; 4. Patients deemed ineligible for enrollment by the investigator.