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UK Heart Failure With Preserved Ejection Fraction
Sponsor: Manchester University NHS Foundation Trust
Summary
Heart failure occurs when the heart is no longer able to pump blood around the body properly. It can cause breathlessness, swollen feet and ankles, and tiredness. In about half of patients with heart failure, one measure of the heart's pumping function, called the 'ejection fraction', is normal. This type of heart failure is called heart failure with preserved ejection fraction, or HFpEF. HFpEF remains poorly understood. It is not clear why some people develop HFpEF, or what determines the severity of the condition. Treatment options may be limited. UK HFpEF is a study that aims to gain a better understanding of why people develop HFpEF, develop better tests to diagnosis it, identify and test new treatments, and follow the health of the people taking part over many years.
Official title: UK Heart Failure With Preserved Ejection Fraction Registry
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
10000
Start Date
2022-10-07
Completion Date
2037-06-01
Last Updated
2025-05-06
Healthy Volunteers
No
Locations (26)
Cwm Taf Morgannwg University Health Board
Abercynon, United Kingdom
Buckinghamshire Healthcare NHS Trust
Aylesbury, United Kingdom
University Hospitals Birmingham NHS Foundation Trust
Birmingham, United Kingdom
Broomfield Hospital
Chelmsford, United Kingdom
NHS Tayside
Dundee, United Kingdom
Glasgow Royal Infirmary
Glasgow, United Kingdom
West Suffolk NHS Foundation Trust
Ipswich, United Kingdom
Kettering General Hospital
Kettering, United Kingdom
Leeds Teaching Hospitals NHS Trust
Leeds, United Kingdom
University Hospitals of Leicester NHS Foundation Trust
Leicester, United Kingdom
Barnet Hospital
London, United Kingdom
Guys and St. Thomas' NHS Foundation Trust
London, United Kingdom
Imperial College Healthcare NHS Trust
London, United Kingdom
Manchester University NHS Foundation trust
Manchester, United Kingdom
The James Cook University Hospital
Middlesbrough, United Kingdom
Northumbria Healthcare NHS Foundation Trust
Newcastle upon Tyne, United Kingdom
Norfolk & Norwich University Hospitals NHS Foundation Trust
Norwich, United Kingdom
George Eliot Hospital
Nuneaton, United Kingdom
North West Anglia NHS Foundation Trust
Peterborough, United Kingdom
University Hospitals Dorset NHS Foundation Trust
Poole, United Kingdom
Betsi Cadwaldr University Health Board
Rhyl, United Kingdom
Salisbury NHS Foundation Trust
Salisbury, United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
Sheffield, United Kingdom
University Hospital of North Tees
Stockton-on-Tees, United Kingdom
South Tyneside & Sunderland NHS Foundation Trust
Sunderland, United Kingdom
Southend University Hospital
Westcliff-on-Sea, United Kingdom