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Disease Activity Biomarkers in Patients With Systemic Lupus Erythematosus
Sponsor: Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Summary
The aim of this research project is to better understand the origin and clinical significance of two lupus-specific "genetic signatures" (IFN signature and plasma cell signature) in patient subgroups with well-defined clinical characteristics. Our aim is to correlate these genetic signatures with cell activation profiles and the production of specific cytokines in different populations from whole blood and in short-term cultures of these circulating cells.
Official title: Disease Activity Biomarkers in Patients With Systemic Lupus Erythematosus. Recherche de Biomarqueurs de l'activité de la Maladie Chez Des Patients Atteints de Lupus érythémateux disséminé.
Key Details
Gender
All
Age Range
18 Years - 70 Years
Study Type
OBSERVATIONAL
Enrollment
250
Start Date
2014-06-16
Completion Date
2032-12-31
Last Updated
2022-07-05
Healthy Volunteers
Not specified
Conditions
Locations (1)
Cliniques universitaires Saint-Luc
Brussels, Belgium