Clinical Research Directory
Browse clinical research sites, groups, and studies.
Physiological-based Pharmacokinetics Approach to Medication Exposure During Pregnancy and Breastfeeding
Sponsor: University of Pittsburgh
Summary
This project focuses on anti-seizure medication (ASM) clearance and physiological factors determining blood concentrations in pregnant adult women with epilepsy and amounts of exposure to their unborn children and nursing infants.
Official title: Physiological-based Pharmacokinetics Approach to Determine the Extent of Drug Exposure of Antiseizure Medications During Pregnancy and Breastfeeding
Key Details
Gender
FEMALE
Age Range
18 Years - 45 Years
Study Type
OBSERVATIONAL
Enrollment
60
Start Date
2022-07-20
Completion Date
2028-04-01
Last Updated
2025-04-18
Healthy Volunteers
No
Conditions
Interventions
Lamotrigine
Anti-seizure concentrations
Levetiracetam
Anti-seizure concentrations
Oxcarbazepine
Anti-seizure concentrations
Locations (1)
University of Pittsburgh
Pittsburgh, Pennsylvania, United States