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Adjuvant Therapy Omission for Resected NSCLC Patients With Longitudinal Undetectable MRD
Sponsor: Guangdong Association of Clinical Trials
Summary
Molecular residual disease (MRD) has strong relationship with clinical outcome in multiple solid tumors. Here, the investigators try to verify the negative predictive value of undetectable MRD, which is considered as a superior prognostic factor for resected NSCLC patients, and not requiring excessive adjuvant therapy. Stage IB-IIIA resected NSCLC patients with landmark and longitudinal undetectable MRD are enrolled and under close surveillance in this study.
Official title: Dynamic Observational Strategy for Stage IB-IIIA Non-Small Cell Lung Cancer Patients After Complete Resection Based on Longitudinal Undetectable Molecular Residual Disease: Prospective, Multicenter, Single-Arm Study
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
180
Start Date
2022-08-01
Completion Date
2026-12-31
Last Updated
2026-09-16
Healthy Volunteers
No
Conditions
Interventions
Molecular residual disease test
OncoMRD Lung
Locations (5)
The First People's Hospital of Foshan
Foshan, Guangdong, China
Guangdong Lung Cancer Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences
Guangzhou, Guangdong, China
Shantou Centeral Hospital
Shantou, Guangdong, China
the First Affiliated Hospital of Shantou University Medical College
Shantou, Guangdong, China
Zhongshan City People's Hospital
Zhongshan, Guangdong, China