Clinical Research Directory

Inclusion Criteria: Control participants: * lifetime absence of major psychiatric illness * 40 to 70 years old * be at risk for or have a diagnosis of obstructive sleep apnea For participants with serious mental illness: * diagnosis of schizophrenia, schizoaffective disorder, or bipolar disorder * must not be conservatized * 40 - 70 years old * be at risk or have a diagnosis of obstructive sleep apnea. Exclusion Criteria: * DSM-IV-TR diagnosis of active alcohol or other substance abuse or dependence in the 3 months preceding enrollment. This will be self-report. * Diagnosis of dementia, mental retardation, or other neurological or medical conditions known to affect neurophysiologic or neurocognitive functioning, or autoimmune disease * Other major DSM-IV-TR Axis I Disorder * Medical problems that interfere with a participant's ability to complete the assessments * Plans to move out of the San Diego county area within the following 6 months * Diagnosis of OSA and currently receiving APAP, CPAP, or any treatment from a physician.