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Multiomic Diagnostics in Youth With Psychosis
Sponsor: Rady Pediatric Genomics & Systems Medicine Institute
Summary
Rady Children's Institute for Genomic Medicine seeks to understand the genomes and immune systems in 15 children and adolescents who are admitted to Rady Children's Hospital Child and Adolescent Psychiatry Service with psychotic symptoms or schizophrenia. Cutting-edge genome and protein sequencing technology will be used to better understand how immunological and genetic assessments may improve our ability to identify the cause of psychosis and impact care. The investigator also hopes to identify new genetic and/or autoimmune causes of psychosis that may inform new treatment for future patients.
Official title: Multiomic Diagnostics in Child and Adolescent Psychosis
Key Details
Gender
All
Age Range
7 Years - 17 Years
Study Type
INTERVENTIONAL
Enrollment
15
Start Date
2022-10-10
Completion Date
2026-08
Last Updated
2024-11-14
Healthy Volunteers
No
Conditions
Interventions
Genetic: Genomic sequencing and molecular diagnostic results, if any.
Genomic sequencing results may be used for diagnosis and treatment of participants.
Phage display ImmunoPrecipiation Sequencing (PhIP-Seq)
Whole Proteome programmable phage display immunoprecipitation sequencing will be used to diagnose known and novel autoantibodies.
Locations (1)
Rady Children's Hospital San Diego
San Diego, California, United States