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Testing Adaptive Interventions to Improve Posttraumatic Stress Disorder Treatment Outcomes in Federally Qualified Health Centers
Sponsor: University of Michigan
Summary
This trial is being completed to develop a stepped-care talk therapy model for patients with PTSD. Specifically, this study is testing whether beginning with one type of therapy is better than beginning with another type of therapy, and whether moving to a different therapy after four sessions is more helpful than staying with the same therapy, depending on how well it is working. The central hypothesis is that beginning with a low- or medium-intensity PTSD intervention and then titrating intensity based on early indications of response will result in clinically significant PTSD symptom reduction with parsimony of resources.
Official title: Testing Adaptive Interventions to Improve Posttraumatic Stress Disorder (PTSD) Treatment Outcomes in Federally Qualified Health Centers
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
430
Start Date
2022-06-23
Completion Date
2026-05
Last Updated
2025-08-14
Healthy Volunteers
No
Conditions
Interventions
Prolonged Exposure for Primary Care (PE-PC)
Treatment follows the standardized PE-PC manual and workbook.PE-PC consists of four weekly 30-minute sessions. In vivo and imaginal exposure are introduced at the first session and reviewed at Sessions 2-4. To conduct in vivo exposure, participants repeatedly and systematically approach objectively safe people, places, objects, and situations that they avoid because these stimuli remind them of their trauma. At the 4th session or 9-week assessment point (whichever comes first), early responders will step down to every-other-week sessions for the duration of the second stage.
Full Prolonged Exposure
Treatment will follow the standardized PE manual. Participants will have 60 minute sessions once a week for eight weeks During these sessions, participants will practice in vivo, imaginal, and emotional exposure as well as continue these exposure exercises every day at home.
Clinician Supported PTSD Coach App
This is a brief psychotherapy that uses the PTSD Coach mobile app developed by the study team. The PTSD Coach app incorporates evidence-based assessment, psychoeducation, and cognitive behavioral therapy and self-management strategies that are customizable to the user.
Locations (13)
Family Health Care
Baldwin, Michigan, United States
Grace Health
Battle Creek, Michigan, United States
Genesee Community Health Center
Flint, Michigan, United States
Hamilton Community Health Network
Flint, Michigan, United States
Cherry Health
Grand Rapids, Michigan, United States
MidMichigan Community Health Services
Houghton Lake, Michigan, United States
Upper Great Lakes Family Health Care Center
Menominee, Michigan, United States
Family Medical Center of Michigan
Monroe, Michigan, United States
Sterling Area Health Center
Sterling, Michigan, United States
Family Care Health Centers
St Louis, Missouri, United States
Western North Carolina Community Health Services
Asheville, North Carolina, United States
CommUnityCare Health Centers
Austin, Texas, United States
Unity Care NW
Bellingham, Washington, United States